Anti-SARS-CoV-2 N-Protein Antibody

Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Nucleocapsid Protein
As low as $115.00
In stock
Only %1 left
Catalog #:
130-10760
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Product Description

Specifications

Size 20 ug, 100 µg, 200 µg, 500 µg, 1000 µg
Host Species Rabbit
Accession Number QHD43423
Protein Name / Synonyms SARS-CoV-2 Nucleocapsid Protein
Clonality Polyclonal
Preparation This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 Nucleocapsid protein. The IgG fraction was purified by Protein A affinity chromatography.
Reconstitution Product is supplied as a powder obtained from lyophilization of purified antibody in 1X PBS, aliquot using ddH2O. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml.
Estimated Lead Time 1-2 business days
Shipping Type Ambient temperature
Storage -20°C

Description

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch.Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways.

Specificity

This antibody was selected for its ability to bind to the virus SARS-CoV-2 Nucleocapsid Protein from the disease COVID-19.

Storage

Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C. Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.
Expiration:
12 months from the date of shipment when stored properly.
McCafferty S, Haque AA, Vandierendonck A, Weidensee B, Plovyt M, Stuchlíková M, François N, Valembois S, Heyndrickx L, Michiels J, Ariën KK. A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity. Molecular Therapy. 2022 Sep 7;30(9):2968-83.
Timilsina SS, Durr N, Jolly P, Ingber DE. Rapid quantitation of SARS-CoV-2 antibodies in clinical samples with an electrochemical sensor. Biosensors and Bioelectronics. 2023 Mar 1;223:115037.
Timilsina SS, Durr N, Jolly P, Ingber DE. Rapid quantitative electrochemical detection of SARS-CoV-2 antibodies in plasma and dried blood spot samples. medRxiv. 2022 Oct 17:2022-10.
Chabi M, Vu B, Brosamer K, Smith M, Chavan D, Conrad JC, Willson R, Kourentzi K. Smartphone-Read Phage Lateral Flow Assay for Point-of-Care Detection of SARS-CoV-2 Infection.
Najjar D, Rainbow J, Sharma Timilsina S, Jolly P, De Puig H, Yafia M, Durr N, Sallum H, Alter G, Li JZ, Yu XG. A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma. Nature biomedical engineering. 2022 Aug;6(8):968-78.
Najjar D, Rainbow J, Timilsina SS, Jolly P, De Puig H, Yafia M, Durr N, Sallum H, Alter G, Li JZ, Yu XG. Lab-on-a-chip multiplexed electrochemical sensor enables simultaneous detection of SARS-CoV-2 RNA and host antibodies. MedRxiv. 2021 Sep 5:2021-09.
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