This DHH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human DHH.
Concentration (lot specific)
0.500 mg/ml
Recommended Applications
Western Blotting
Estimated Lead Time
1-2 weeks
Shipping Type
Blue ice
Storage
-20°C
Introduction
This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Specificity
Predicted Reactivity
Mouse
Other Names
DHH; Desert hedgehog protein; HHG-3; Desert hedgehog protein N-product; Desert hedgehog protein C-product
DHH Antibody (Center) (Cat# 102-14168) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the DHH antibody detected the DHH protein (arrow).
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
