MHC class I molecules are expressed on the cell surface of all nucleated cells in humans. This antibody recognizes human HLA-A, B, C. MHC class I consists of three α units (α1, α2, and α3) and one β unit (β2 microglobulin). These units interact with a CD8 T cell receptor complex and present non-self antigenic peptide which triggers an immediate response from the immune system against a particular non-self antigen. Human MHC class I play an important role in cell-mediated immune responses and tumor surveillance.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.
