This antibody was produced from antiserum of rabbits immunized with a recombinant APP (Ab42) protein. The IgG fraction was purified by Protein A affinity chromatography.
Recommended Applications
ELISA (recommended work dilution = 1:10,000)
Reconstitution
Product is supplied as a powder obtained from lyophilization of purified antibody in glycine solution. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml.
Estimated Lead Time
1-2 business days
Shipping Type
Blue ice
Storage
-20°C
Description
β-amyloid protein (Aβ or Abeta) is a series of protein peptides formed by the cleavage of amyloid precursor protein (APP) by β- and γ- secretases, and is believed to be associated with the pathogenesis of Alzheimer's disease. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue. Evidence suggests that beta amyloid protein 42 plasma levels are associated with Alzheimer's disease.
Storage/Stability
Store at -20°C. If intended for use within a month, may keep at 4°C. Minimize freeze-thaw cycles.
Expiration
12 months from the date of shipment when stored properly.
